※ Fer family introduction

    Fer is nonontransmembrane receptor tyrosine kinases accepting the signal from cell surface receptors including EGFR, PDGFRA and PDGFRB and regulating a variety of cell processes. Interaction with EGFR will lead to the activation of NF-kappa-B pathway and cell proliferation. Fer can act as a downstream protein of activated FCER1 receptor and plays an important role in FCER1-mediated signaling in mast cells. Fer can also mediate phosphorylation of several substrates including, CTNND1, CTTN, PTK2/FAK1, PECAM1, GAB1 and PTPN11 (1).

Reference
1. UniProt Annotation:     FER_HUMAN

  Reviewed (0)  or Unreviewed (2) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tag-1279	ENSTGUG00000000963.1	H0YRT1	FER
2		iEKPD-Tag-1297	ENSTGUG00000010113.1	H0ZIM7	FES