Rattus norvegicus      TK/Lmr


※ Lmr family introduction

    Lmr (Lemur tyrosine kinase) belong to tyrosine kinase family (1). Three members have been found in human genome. LMTK1, also known as AATK, is an apoptosis-associated tyrosine kinase; it contains an N-terminal tyrosine kinase domain and a C-terminal proline-rich domain. LMTK1 is required for induction of growth arrest or apoptosis of myeloid precursor cells. LMTK2 is thought to mediate the phosphorylation of PPP1C. Function and regulation LMTK3 remain further understood (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikipedia annotation:    AATK


There are 2 genes.  Reviewed (0 or Unreviewed (2

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ran-0073
ENSRNOG00000004392.5
D4ABZ3
Aatk
2
iEKPD-Ran-0364
ENSRNOG00000025155.6
D3ZBH5
Lmtk2