※ MLK family introduction

    MLKs (Mixed-lineage kinases) are ser/thr protein kinases which are involved in regulation of JNK and p38 MAPK pathways. MLKs contains threes subfamily, MLK, DLK and ZAK. MLK subfamily is characterized by an N-terminal SH3 domain, followed by a protein kinase domain, a leucine-zipper region and a CRIB motif. DLK subfamily contains a kinase domain and two leucine-zipper motifs. ZAK subfamily consists of a kinase domain and a SAM domain. MLKs play an important role in regulation of JNK pathways in mammalian cells which will result in diverse biological processes, including cellular transformation, activation of NF-kB pathways, neuronal apoptosis and so on (1).

Reference
1. Gallo, K.A. and Johnson, G.L. (2002) Mixed-lineage kinase control of JNK and p38 MAPK pathways. Nat Rev Mol Cell Biol, 3, 663-672. PMID: 12209126

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Glm-0524	GLYMA_06G020200
2		iEKPD-Glm-0529	GLYMA_06G042500
3		iEKPD-Glm-0554	GLYMA_06G097700
4		iEKPD-Glm-0587	GLYMA_06G182900
5		iEKPD-Glm-0890	GLYMA_08G237200
6		iEKPD-Glm-0950	GLYMA_09G006900
7		iEKPD-Glm-0986	GLYMA_09G095900
8		iEKPD-Glm-0997	GLYMA_09G119600
9		iEKPD-Glm-1048	GLYMA_09G241500
10		iEKPD-Glm-1108	GLYMA_10G104500
11		iEKPD-Glm-1162	GLYMA_10G245600
12		iEKPD-Glm-1414	GLYMA_12G233200
13		iEKPD-Glm-1625	GLYMA_14G047900
14		iEKPD-Glm-1763	GLYMA_15G120600
15		iEKPD-Glm-1780	GLYMA_15G169400
16		iEKPD-Glm-1854	GLYMA_16G064200
17		iEKPD-Glm-1855	GLYMA_16G064400
18		iEKPD-Glm-1862	GLYMA_16G065500
19		iEKPD-Glm-1863	GLYMA_16G0656002
20		iEKPD-Glm-1864	GLYMA_16G065700
21		iEKPD-Glm-1896	GLYMA_16G141600
22		iEKPD-Glm-2175	GLYMA_19G002800
23		iEKPD-Glm-2240	GLYMA_19G191600
24		iEKPD-Glm-2335	GLYMA_20G165800
25		iEKPD-Glm-2375	GLYMA_U024800
26		iEKPD-Glm-0105	GLYMA_02G021700	C6ZRY6	100305443
27		iEKPD-Glm-1091	GLYMA_10G066000	K7LHS5	100775768
28		iEKPD-Glm-1793	GLYMA_15G202000	K7MCM1	100776264
29		iEKPD-Glm-0834	GLYMA_08G123800	I1KSM4	100777862
30		iEKPD-Glm-0517	GLYMA_05G245300	I1K5D0	100778331
31		iEKPD-Glm-0438	GLYMA_05G037200	K7KMQ1	100778530
32		iEKPD-Glm-1193	GLYMA_11G018800	K7LML2	100778844
33		iEKPD-Glm-1461	GLYMA_13G094500	K7LWW4	100779077
34		iEKPD-Glm-2016	GLYMA_17G229100	K7MNG9	100779137
35		iEKPD-Glm-1691	GLYMA_14G197000	K7M829	100779427
36		iEKPD-Glm-1642	GLYMA_14G094400	I1M918	100779790
37		iEKPD-Glm-0794	GLYMA_08G052700	I1KQJ4	100780884
38		iEKPD-Glm-2089	GLYMA_18G198000	K7MTF4	100780938
39		iEKPD-Glm-1828	GLYMA_15G270700	K7ME59	100782673
40		iEKPD-Glm-1149	GLYMA_10G226300	K7LKX4	100782737
41		iEKPD-Glm-1938	GLYMA_17G065700	K7MK79	100782903
42		iEKPD-Glm-0837	GLYMA_08G126000	I1KSP8	100784109
43		iEKPD-Glm-1829	GLYMA_15G271100	K7ME61	100784279
44		iEKPD-Glm-0753	GLYMA_07G197200	I1KLK5	100784454
45		iEKPD-Glm-1853	GLYMA_16G064100	I1MLP8	100784831
46		iEKPD-Glm-1950	GLYMA_17G090000	K7MKQ8	100785212
47		iEKPD-Glm-1923	GLYMA_17G033700	I1MRR0	100785569
48		iEKPD-Glm-1683	GLYMA_14G182700	K7M7T5	100786546
49		iEKPD-Glm-0162	GLYMA_02G203600	K7K9R1	100787157
50		iEKPD-Glm-0298	GLYMA_03G191000	I1JPX3	100787894
51		iEKPD-Glm-1952	GLYMA_17G090600	I1MTI4	100788033
52		iEKPD-Glm-0782	GLYMA_08G026500	I1KPP1	100788536
53		iEKPD-Glm-0831	GLYMA_08G117000	I1KSF2	100788556
54		iEKPD-Glm-1018	GLYMA_09G177600	I1L468	100788742
55		iEKPD-Glm-0024	GLYMA_01G052600	I1J5U2	100789273
56		iEKPD-Glm-1752	GLYMA_15G088500	A0A0R0G676	100790126
57		iEKPD-Glm-0941	GLYMA_08G356500	K7LAT7	100790135
58		iEKPD-Glm-0388	GLYMA_04G182700	I1JX70	100791455
59		iEKPD-Glm-0570	GLYMA_06G145500	I1KBA7	100791498
60		iEKPD-Glm-0193	GLYMA_02G263900	I1JIF1	100792450
61		iEKPD-Glm-0423	GLYMA_05G002600	I1K1M3	100792887
62		iEKPD-Glm-2258	GLYMA_20G031300	A0A0R4J632	100793237
63		iEKPD-Glm-1644	GLYMA_14G099300	K7M5Y7	100794498
64		iEKPD-Glm-0206	GLYMA_02G288300	I1JJ60	100795964
65		iEKPD-Glm-0586	GLYMA_06G177700	I1KCB5	100796593
66		iEKPD-Glm-1491	GLYMA_13G169300	I1M016	100796762
67		iEKPD-Glm-1690	GLYMA_14G196600	K7M826	100798384
68		iEKPD-Glm-0850	GLYMA_08G165800	I1KTY1	100799118
69		iEKPD-Glm-0769	GLYMA_07G264700	K7L3Y6	100799437
70		iEKPD-Glm-0238	GLYMA_03G036000	I1JKY2	100799533
71		iEKPD-Glm-0851	GLYMA_08G165900	I1KTY2	100799639
72		iEKPD-Glm-1484	GLYMA_13G151100	I1LZF4	100800648
73		iEKPD-Glm-0764	GLYMA_07G239600	I1KMQ9	100800867
74		iEKPD-Glm-0176	GLYMA_02G229900	I1JHG3	100801110
75		iEKPD-Glm-1253	GLYMA_11G167100	K7LQZ3	100801161
76		iEKPD-Glm-1823	GLYMA_15G261100	I1MJC0	100801946
77		iEKPD-Glm-0507	GLYMA_05G220200	A0A0R0K7C0	100802077
78		iEKPD-Glm-0407	GLYMA_04G220400	I1JY96	100802768
79		iEKPD-Glm-1824	GLYMA_15G261200	I1MJC1	100802996
80		iEKPD-Glm-1918	GLYMA_17G009300	K7MJC2	100803225
81		iEKPD-Glm-0063	GLYMA_01G161600	I1J8F7	100803377
82		iEKPD-Glm-1402	GLYMA_12G211000	K7LW65	100803469
83		iEKPD-Glm-0092	GLYMA_01G236100	I1JAR3	100803917
84		iEKPD-Glm-2275	GLYMA_20G105300	I1NF71	100804170
85		iEKPD-Glm-1577	GLYMA_13G341100	A0A0R4J549	100804210
86		iEKPD-Glm-0390	GLYMA_04G188200	I1JXB8	100804884
87		iEKPD-Glm-1762	GLYMA_15G113500	K7MAU1	100806033
88		iEKPD-Glm-1509	GLYMA_13G223400	I1M1M4	100806334
89		iEKPD-Glm-0643	GLYMA_06G276900	I1KEM9	100806527
90		iEKPD-Glm-0597	GLYMA_06G221400	I1KDD2	100807051
91		iEKPD-Glm-1343	GLYMA_12G128700	K7LUH0	100807193
92		iEKPD-Glm-2348	GLYMA_20G197800	K7N4J1	100807361
93		iEKPD-Glm-1514	GLYMA_13G228300	I1M1S5	100807390
94		iEKPD-Glm-0143	GLYMA_02G165800	K7K8Z6	100807496
95		iEKPD-Glm-2325	GLYMA_20G149000	I1NGI3	100807899
96		iEKPD-Glm-0437	GLYMA_05G036600	I1JZZ2	100807921
97		iEKPD-Glm-1815	GLYMA_15G237200	K7MDH1	100808316
98		iEKPD-Glm-1865	GLYMA_16G069200	I1MLT0	100808329
99		iEKPD-Glm-0359	GLYMA_04G096000	I1JV83	100808435
100		iEKPD-Glm-1067	GLYMA_09G275900	K7LGH0	100809251
101		iEKPD-Glm-2206	GLYMA_19G081200	I1N7J0	100809509
102		iEKPD-Glm-2192	GLYMA_19G056300	I1N6Z2	100809826
103		iEKPD-Glm-0588	GLYMA_06G183500	I1KCH4	100809898
104		iEKPD-Glm-2081	GLYMA_18G174200	I1N2C5	100809991
105		iEKPD-Glm-0952	GLYMA_09G009100	K7LB63	100810171
106		iEKPD-Glm-0488	GLYMA_05G167600	K7KQN9	100810411
107		iEKPD-Glm-0532	GLYMA_06G055300	K7KT98	100810435
108		iEKPD-Glm-1557	GLYMA_13G290400	I1M3L5	100810612
109		iEKPD-Glm-1137	GLYMA_10G192700	K7LKC2	100810711
110		iEKPD-Glm-2054	GLYMA_18G058800	I1MZW2	100811417
111		iEKPD-Glm-1613	GLYMA_14G026700	A0A0R0G8Z7	100812598
112		iEKPD-Glm-1841	GLYMA_16G027300	K7MEW9	100813704
113		iEKPD-Glm-0084	GLYMA_01G217100	K7K556	100813707
114		iEKPD-Glm-0846	GLYMA_08G151400	K7L6V4	100814245
115		iEKPD-Glm-0965	GLYMA_09G035400	I1L0Q6	100815858
116		iEKPD-Glm-0760	GLYMA_07G228000	I1KMF4	100815995
117		iEKPD-Glm-0714	GLYMA_07G101600	I1KJ44	100816332
118		iEKPD-Glm-1802	GLYMA_15G213400	I1MI76	100816522
119		iEKPD-Glm-0047	GLYMA_01G132300	K7K3L6	100816708
120		iEKPD-Glm-1222	GLYMA_11G082200	I1LI72	100816767
121		iEKPD-Glm-0330	GLYMA_04G041400	I1JTL8	100817172
122		iEKPD-Glm-1124	GLYMA_10G159200	I1LBH2	100817822
123		iEKPD-Glm-0325	GLYMA_04G020100	K7KHP1	100818047
124		iEKPD-Glm-2361	GLYMA_20G229500	I1NIU9	100818780
125		iEKPD-Glm-1252	GLYMA_11G166000	I1LLR0	100819097
126		iEKPD-Glm-1959	GLYMA_17G105100	I1MTZ3	100819234
127		iEKPD-Glm-1631	GLYMA_14G057400	I1M7R5	100820416
128		iEKPD-Glm-1190	GLYMA_11G007100	I1LFV0	100820513
129		iEKPD-Glm-2014	GLYMA_17G225400	K7MNE4	102666416
130		iEKPD-Glm-0181	GLYMA_02G237200	K7KAC6	GLYMA_02G237200
131		iEKPD-Glm-0617	GLYMA_06G257200	K7KXD4	GLYMA_06G257200
132		iEKPD-Glm-0685	GLYMA_07G058300	K7KZW6	GLYMA_07G058300
133		iEKPD-Glm-1050	GLYMA_09G243400	K7LFU5	GLYMA_09G243400
134		iEKPD-Glm-1262	GLYMA_11G196800	K7LQE3	GLYMA_11G196800
135		iEKPD-Glm-1330	GLYMA_12G077500	I1LR55	GLYMA_12G077500
136		iEKPD-Glm-1371	GLYMA_12G152400	K7LV24	GLYMA_12G152400
137		iEKPD-Glm-1858	GLYMA_16G065000	K7MFI7	GLYMA_16G065000
138		iEKPD-Glm-1861	GLYMA_16G065400	K7K0X1	GLYMA_16G065400
139		iEKPD-Glm-1745	GLYMA_15G074900	Q39886	PK6