※ STKR family introduction

    STKR are serine/threonine kinase receptor comprising two subfamily, TGFb receptors and activin receptors. TGFb receptors contain different isoforms which are homo- or heterodimeric. The mediate the interaction between ligand and receptor. TGFb receptors are expressed in diverse tissues, including heart, liver, kidney, brain and testes. TGFb receptor can be further classified into three subclasses from type1 to type3. Abnormal expression of TGFb receptor leads to renal fibrosis which will result in kidney disease. Diabetes is also found to be associated with TGFb receptor (1). Another subfamily is activin receptors, which are characterized by its feature to bind activin. The activin receptors contain a transmembrane domain and a hydrophilic Cys-rich ligand-binding domain (2).

Reference
1. Wikipedia annotation: TGF beta receptors
2. Wikipedia annotation: Activin receptor

  Reviewed (0)  or Unreviewed (12) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Dan-0047	ENSDNOG00000004277.3
2		iEKPD-Dan-0117	ENSDNOG00000008783.3
3		iEKPD-Dan-0129	ENSDNOG00000009781.3
4		iEKPD-Dan-0161	ENSDNOG00000012570.2
5		iEKPD-Dan-0176	ENSDNOG00000013862.3
6		iEKPD-Dan-0218	ENSDNOG00000016718.2
7		iEKPD-Dan-0219	ENSDNOG00000016742.3
8		iEKPD-Dan-0245	ENSDNOG00000018434.3
9		iEKPD-Dan-0279	ENSDNOG00000031774.1
10		iEKPD-Dan-0308	ENSDNOG00000034270.1
11		iEKPD-Dan-0330	ENSDNOG00000036661.1
12		iEKPD-Dan-0419	ENSDNOG00000044427.1