Brassica rapa      (pS/pT)/14-3-3


※ 14-3-3 family introduction

    14-3-3 proteins constitute a highly conserved family of homo- and heterodimeric molecules present in high abundance in eukaryotic cells. The proteins of 14-3-3 family mediate signal transduction by binding to phosphoserine-containing proteins. Through interacting with Cdc25C, 14-3-3 regulates entry into the cell cycle . 14-3-3 interacts with BAD preventing apoptosis by releasing Bcl-XL . In addition, 14-3-3 proteins interact with other signaling molecules including members of the protein kinase C family , Cbl , IRS1 , and polyoma middle-T antigen (1).

Reference
1. Yaffe, M.B., Rittinger, K. (1997) The structural basis for 14-3-3:phosphopeptide binding specificity. Cell, 91, 961-71. PMID: 9428519


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Brr-1927
Bra028187
M4EHC2
2
iEKPD-Brr-1928
Bra028409
M4EHZ4
3
iEKPD-Brr-1929
Bra040592
M4FHL4
4
iEKPD-Brr-1930
Bra035027
M4F1T0
5
iEKPD-Brr-1931
Bra028068
M4EH03
6
iEKPD-Brr-1932
Bra008355
M4CVV8
7
iEKPD-Brr-1933
Bra003649
M4CHG6
8
iEKPD-Brr-1934
Bra001049
M4CA20
9
iEKPD-Brr-1935
Bra034430
M4F037
10
iEKPD-Brr-1936
Bra031383
M4ERF9
11
iEKPD-Brr-1937
Bra037818
M4F9Q5
12
iEKPD-Brr-1938
Bra024384
M4E6I0