Oryza sativa      (pS/pT)/14-3-3


※ 14-3-3 family introduction

    14-3-3 proteins constitute a highly conserved family of homo- and heterodimeric molecules present in high abundance in eukaryotic cells. The proteins of 14-3-3 family mediate signal transduction by binding to phosphoserine-containing proteins. Through interacting with Cdc25C, 14-3-3 regulates entry into the cell cycle . 14-3-3 interacts with BAD preventing apoptosis by releasing Bcl-XL . In addition, 14-3-3 proteins interact with other signaling molecules including members of the protein kinase C family , Cbl , IRS1 , and polyoma middle-T antigen (1).

Reference
1. Yaffe, M.B., Rittinger, K. (1997) The structural basis for 14-3-3:phosphopeptide binding specificity. Cell, 91, 961-71. PMID: 9428519


There are 5 genes.  Reviewed (5 or Unreviewed (0

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ors-1449
Os04g0462500
Q7XTE8
GF14B; Os04g0462500; LOC_Os04g38870; B0812A04.1; B1358B12.12; OSJNBa0072F16.20
2
iEKPD-Ors-1450
Os08g0430500
Q6ZKC0
GF14C; Os08g0430500; LOC_Os08g33370; OJ1124_B05.7
3
iEKPD-Ors-1452
Os11g0546900
Q2R2W2
GF14D; Os11g0546900; LOC_Os11g34450; OsJ_34200
4
iEKPD-Ors-1448
Os02g0580300
Q6EUP4
GF14E; Os02g0580300; LOC_Os02g36974; B1267B06.30-1; OJ1115_A05.5-1; OsJ_07268
5
iEKPD-Ors-1451
Os03g0710800
Q06967
GF14F; Os03g0710800; LOC_Os03g50290; OsJ_12311