Solanum tuberosum      (pS/pT)/14-3-3


※ 14-3-3 family introduction

    14-3-3 proteins constitute a highly conserved family of homo- and heterodimeric molecules present in high abundance in eukaryotic cells. The proteins of 14-3-3 family mediate signal transduction by binding to phosphoserine-containing proteins. Through interacting with Cdc25C, 14-3-3 regulates entry into the cell cycle . 14-3-3 interacts with BAD preventing apoptosis by releasing Bcl-XL . In addition, 14-3-3 proteins interact with other signaling molecules including members of the protein kinase C family , Cbl , IRS1 , and polyoma middle-T antigen (1).

Reference
1. Yaffe, M.B., Rittinger, K. (1997) The structural basis for 14-3-3:phosphopeptide binding specificity. Cell, 91, 961-71. PMID: 9428519


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sot-1339
PGSC0003DMG400017753
M1BI71
2
iEKPD-Sot-1340
PGSC0003DMG400019587
M1BQ79
3
iEKPD-Sot-1343
PGSC0003DMG400016221
M1BC18
4
iEKPD-Sot-1341
PGSC0003DMG400024187
M1C8L3
102579744
5
iEKPD-Sot-1344
PGSC0003DMG400006415
M1A7M4
102581950; St14a
6
iEKPD-Sot-1345
PGSC0003DMG400020425
M1BTP6
102596432; St14h
7
iEKPD-Sot-1338
PGSC0003DMG400030814
P93786
34G; 102582707
8
iEKPD-Sot-1342
PGSC0003DMG400023590
Q6R2P7
St14i