Arabidopsis thaliana      (pS/pT)/BRCT


※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982


There are 20 genes.  Reviewed (13 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Art-1221
AT4G02110
O04251
At4g02110; T10M13.12
2
iEKPD-Art-1228
AT1G04020
F4I443
BARD1; ROW1; At1g04020; F21M11.4
3
iEKPD-Art-1227
AT4G21070
Q8RXD4
BRCA1; At4g21070; T13K14.230
4
iEKPD-Art-1545
AT2G33540
Q8LL04
CPL3; At2g33540; F4P9.31
5
iEKPD-Art-1544
AT5G58003
Q00IB6
CPL4; At5g58003; MTI20
6
iEKPD-Art-1224
AT5G57160
Q9LL84
LIG4; At5g57160; MUL3.11
7
iEKPD-Art-1235
AT2G31320
Q9ZP54
PARP1; At2g31320; F16D14.16
8
iEKPD-Art-1229
AT5G22470
Q9FK91
PARP3; At5g22470; MQJ16_1
9
iEKPD-Art-1236
AT5G14520
Q9LYK7
PES; At5g14520; T15N1_10
10
iEKPD-Art-1237
AT1G10520
Q9FNY4
POLL; At1g10520; T10O24.13
11
iEKPD-Art-1231
AT5G44750
A3EWL3
REV1; At5g44750; K23L20.9; T19K24.14
12
iEKPD-Art-1233
AT5G22010
Q9C587
RFC1; At5g22010; T6G21
13
iEKPD-Art-1226
AT1G80420
Q24JK4
XRCC1; At1g80420; T21F11.25
14
iEKPD-Art-1232
AT1G67180
Q9ZW89
At1g67180; F5A8.9; F5A8_9
15
iEKPD-Art-1222
AT2G26270
F4ITP1
At2g26270; T1D16.9; T1D16_9
16
iEKPD-Art-1223
AT2G41450
B3H6L5
At2g41450; T26J13.4; T26J13_4
17
iEKPD-Art-1234
AT3G21480
Q9LVF7
At3g21480
18
iEKPD-Art-1225
AT3G43930
Q6DSR3
At3g43930
19
iEKPD-Art-1230
AT4G03130
A0A1P8B7K8
At4g03130; F4C21.5; F4C21_5
20
iEKPD-Art-1220
AT1G77320
A0A1P8AWF3
MEI1; meiosis defective 1; At1g77320; F2P24.3; F2P24_3