※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

  Reviewed (2)  or Unreviewed (8) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Asg-0144	AGOS_ACR008W	Q75CA4	LIG4; ACR008W
2		iEKPD-Asg-0148	AGOS_AAR094W	Q75EI5	NOP7; AAR094W
3		iEKPD-Asg-0253	AGOS_ABL127W	Q75E00	AGOS_ABL127W
4		iEKPD-Asg-0142	AGOS_ADL145C	Q75AR5	AGOS_ADL145C
5		iEKPD-Asg-0146	AGOS_ADR369C	Q759A8	AGOS_ADR369C
6		iEKPD-Asg-0149	AGOS_AEL039W	Q757Q1	AGOS_AEL039W
7		iEKPD-Asg-0150	AGOS_AER402C	Q755W6	AGOS_AER402C
8		iEKPD-Asg-0143	AGOS_AFR095C	Q754I1	AGOS_AFR095C
9		iEKPD-Asg-0147	AGOS_AGL051C	Q750K2	AGOS_AGL051C
10		iEKPD-Asg-0145	AGOS_AGR173C	Q74ZM5	AGOS_AGR173C