※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Asc-0188	CADACLAG00000239	A1C4T6	ACLA_001150
2		iEKPD-Asc-0190	CADACLAG00000875	A1CA63	ACLA_010570
3		iEKPD-Asc-0189	CADACLAG00001413	A1CBF1	ACLA_015070
4		iEKPD-Asc-0186	CADACLAG00001245	A1CBS3	ACLA_016370
5		iEKPD-Asc-0193	CADACLAG00001761	A1CPF4	ACLA_022390
6		iEKPD-Asc-0316	CADACLAG00003381	A1CKP2	ACLA_039310
7		iEKPD-Asc-0187	CADACLAG00004544	A1CIF3	ACLA_051300
8		iEKPD-Asc-0191	CADACLAG00008163	A1CTQ2	ACLA_083840
9		iEKPD-Asc-0192	CADACLAG00009131	A1CMR8	ACLA_097970