Aspergillus fumigatus      (pS/pT)/BRCT


※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982


There are 11 genes.  Reviewed (1 or Unreviewed (10

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ass-0176
CADAFUAG00006159
Q4WVG8
lig4; AFUA_5G12050
2
iEKPD-Ass-0180
CADAFUAG00006899
Q4WSE2
AFUA_1G13080
3
iEKPD-Ass-0181
CADAFUAG00004173
Q4X229
AFUA_2G07890
4
iEKPD-Ass-0182
CADAFUAG00004386
Q4X0U9
AFUA_2G12220
5
iEKPD-Ass-0313
CADAFUAG00005206
Q4WY13
AFUA_3G11410
6
iEKPD-Ass-0173
CADAFUAG00008036
Q4WQC2
AFUA_4G12310
7
iEKPD-Ass-0175
CADAFUAG00002666
Q4WES3
AFUA_5G04020
8
iEKPD-Ass-0177
CADAFUAG00006311
Q4WU62
AFUA_5G07320
9
iEKPD-Ass-0174
CADAFUAG00006303
Q4WVU8
AFUA_5G13380
10
iEKPD-Ass-0178
CADAFUAG00000440
Q4WCU9
AFUA_6G02510
11
iEKPD-Ass-0179
CADAFUAG00001766
Q4WMV6
AFUA_6G08570