※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

  Reviewed (1)  or Unreviewed (8) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Asa-0164	CADANIAG00002653	Q5BH83	lig4; AN0097
2		iEKPD-Asa-0297	CADANIAG00010187	Q5B978	ANIA_02902
3		iEKPD-Asa-0168	CADANIAG00009945	G5EB68	ANIA_03129
4		iEKPD-Asa-0167	CADANIAG00004788	Q5B6C1	ANIA_03909
5		iEKPD-Asa-0169	CADANIAG00006691	Q5AZI2	ANIA_06298
6		iEKPD-Asa-0163	CADANIAG00007698	Q5AXT4	ANIA_06896
7		iEKPD-Asa-0165	CADANIAG00004313	Q5ATX5	ANIA_08255
8		iEKPD-Asa-0166	CADANIAG00006360	Q5ASM0	ANIA_08710
9		iEKPD-Asa-0162	CADANIAG00005074	C8V3U9	ANIA_10434