※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Ast-0196	CADATEAG00007479	Q0CW63	ATEG_02071
2		iEKPD-Ast-0195	CADATEAG00008293	Q0CT69	ATEG_03115
3		iEKPD-Ast-0197	CADATEAG00006917	Q0CPK1	ATEG_04383
4		iEKPD-Ast-0325	CADATEAG00009920	Q0CNQ7	ATEG_04677
5		iEKPD-Ast-0200	CADATEAG00000386	Q0CKJ0	ATEG_05794
6		iEKPD-Ast-0194	CADATEAG00001466	Q0CJG5	ATEG_06169
7		iEKPD-Ast-0199	CADATEAG00003221	Q0CGJ0	ATEG_07202
8		iEKPD-Ast-0198	CADATEAG00005291	Q0CE74	ATEG_08010