※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

  Reviewed (4)  or Unreviewed (5) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Cae-0576	WBGene00000264	B6VQ60	brc-1; C36A4.8
2		iEKPD-Cae-0833	WBGene00009479	Q95QG8	fcp-1; F36F2.6
3		iEKPD-Cae-0574	WBGene00002027	Q7JKP6	hsr-9; T05F1.6
4		iEKPD-Cae-0577	WBGene00003063	Q95Y89	lpd-7; R13A5.12
5		iEKPD-Cae-0578	WBGene00018327	O44486	CELE_F42A6.5; F42A6.5
6		iEKPD-Cae-0573	WBGene00012236	Q9XUM4	CELE_W04A8.1; W04A8.1
7		iEKPD-Cae-0575	WBGene00002297	Q9U364	ect-2; CELE_T19E10.1; T19E10.1
8		iEKPD-Cae-0571	WBGene00009507	Q20129	mus-101; CELE_F37D6.1; F37D6.1
9		iEKPD-Cae-0572	WBGene00004031	Q9U370	pis-1; CELE_T13F2.3; T13F2.3