※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Cas-0634	ENSTSYG00000006130.2	A0A1U7T0M9	BARD1
2		iEKPD-Cas-1230	ENSTSYG00000007557.2	A0A1U7TR57	CTDP1
3		iEKPD-Cas-0635	ENSTSYG00000014760.2	A0A1U7V2I5	ECT2
4		iEKPD-Cas-0642	ENSTSYG00000030927.1	A0A1U7T7W4	LOC103252213
5		iEKPD-Cas-0638	ENSTSYG00000027326.1	A0A1U7SQL8	LOC103253707
6		iEKPD-Cas-0636	ENSTSYG00000033222.1	A0A1U7UIY4	MCPH1
7		iEKPD-Cas-1236	ENSTSYG00000002041.2	A0A1U7TQQ1	NBN
8		iEKPD-Cas-0641	ENSTSYG00000003699.2	A0A1U7TR05	PARP1
9		iEKPD-Cas-0637	ENSTSYG00000014701.2	A0A1U7TAH9	PARP4
10		iEKPD-Cas-0631	ENSTSYG00000006031.2	A0A1U7UL82	PAXIP1
11		iEKPD-Cas-0644	ENSTSYG00000009798.2	A0A1U7TD93	PES1
12		iEKPD-Cas-0643	ENSTSYG00000030944.1	A0A1U7T9C5	POLL
13		iEKPD-Cas-0640	ENSTSYG00000011917.2	A0A1U7TNK1	REV1
14		iEKPD-Cas-0639	ENSTSYG00000013946.2	A0A1U7UQ31	RFC1
15		iEKPD-Cas-0630	ENSTSYG00000004294.2	A0A1U7TT09	TOPBP1
16		iEKPD-Cas-0632	ENSTSYG00000004830.2	A0A1U7TVW0	TP53BP1
17		iEKPD-Cas-0633	ENSTSYG00000014653.2	A0A1U7SNG8	XRCC1