Chlamydomonas reinhardtii      (pS/pT)/BRCT


※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Chr-0848
CHLREDRAFT_187332
A8HYX3
CGL55; CHLREDRAFT_187332
2
iEKPD-Chr-0653
CHLREDRAFT_149108
A8J3F1
CHLREDRAFT_149108
3
iEKPD-Chr-0652
CHLREDRAFT_150878
A8J835
CHLREDRAFT_150878
4
iEKPD-Chr-0648
CHLREDRAFT_174508
A8J3K0
CHLREDRAFT_174508
5
iEKPD-Chr-0649
CHLREDRAFT_175752
A8J7G4
CHLREDRAFT_175752
6
iEKPD-Chr-0655
CHLREDRAFT_178271
A8JCL3
CHLREDRAFT_178271
7
iEKPD-Chr-0650
CHLREDRAFT_96394
A8JHX2
CHLREDRAFT_96394
8
iEKPD-Chr-0651
CHLREDRAFT_173359
A8IYH8
REV1; CHLREDRAFT_173359
9
iEKPD-Chr-0654
CHLREDRAFT_150793
A8J5W8
RFC1; CHLREDRAFT_150793