※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Coh-0208	CH063_00692	H1W5B8	CH063_00692; CH63R_09015
2		iEKPD-Coh-0341	CH063_01096	H1V1V8	CH063_01096
3		iEKPD-Coh-0206	CH063_02219	H1VHZ9	CH063_02219; CH63R_03650
4		iEKPD-Coh-0201	CH063_03748	H1W0G1	CH063_03748
5		iEKPD-Coh-0339	CH063_03896	H1W239	CH063_03896
6		iEKPD-Coh-0207	CH063_05004	H1UXG3	CH063_05004; CH63R_00714
7		iEKPD-Coh-0200	CH063_06294	H1V210	CH063_06294; CH63R_01865
8		iEKPD-Coh-0203	CH063_06312	H1V234	CH063_06312; CH63R_07397
9		iEKPD-Coh-0210	CH063_06634	H1V395	CH063_06634; CH63R_14117
10		iEKPD-Coh-0202	CH063_06642	H1V3A2	CH063_06642; CH63R_02092
11		iEKPD-Coh-0211	CH063_06820	H1V3W3	CH063_06820; CH63R_06019
12		iEKPD-Coh-0204	CH063_07868	H1V7Q0	CH063_07868
13		iEKPD-Coh-0205	CH063_15449	H1W2U6	CH063_15449
14		iEKPD-Coh-0209	CH063_10663	A0A1B7YNJ8	CH63R_02363