※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Fup-0186	FPSE_00173	K3VVC9	FPSE_00173
2		iEKPD-Fup-0187	FPSE_03056	K3W217	FPSE_03056
3		iEKPD-Fup-0191	FPSE_05088	K3VMA5	FPSE_05088
4		iEKPD-Fup-0190	FPSE_06131	K3VJN6	FPSE_06131
5		iEKPD-Fup-0183	FPSE_06477	K3W007	FPSE_06477
6		iEKPD-Fup-0185	FPSE_07305	K3VHV3	FPSE_07305
7		iEKPD-Fup-0184	FPSE_09017	K3VYL6	FPSE_09017
8		iEKPD-Fup-0323	FPSE_10001	K3UE51	FPSE_10001
9		iEKPD-Fup-0188	FPSE_11562	K3V5Q8	FPSE_11562
10		iEKPD-Fup-0189	FPSE_12285	K3VWH8	FPSE_12285