※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mel-0363	MELLADRAFT_115868	F4RF39	MELLADRAFT_115868
2		iEKPD-Mel-0237	MELLADRAFT_26215	F4RMM5	MELLADRAFT_26215
3		iEKPD-Mel-0235	MELLADRAFT_35660	F4RK38	MELLADRAFT_35660
4		iEKPD-Mel-0234	MELLADRAFT_73003	F4S1V0	MELLADRAFT_73003
5		iEKPD-Mel-0233	MELLADRAFT_74693	F4RJK1	MELLADRAFT_74693
6		iEKPD-Mel-0232	MELLADRAFT_78268	F4RSB3	MELLADRAFT_78268
7		iEKPD-Mel-0236	MELLADRAFT_90918	F4R813	MELLADRAFT_90918
8		iEKPD-Mel-0238	MELLADRAFT_94168	F4S6Q6	NOP7; MELLADRAFT_94168