※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mod-1295	ENSMODG00000015873.2	F7BR78
2		iEKPD-Mod-0655	ENSMODG00000012092.2	F7G4N9
3		iEKPD-Mod-0648	ENSMODG00000015631.3	F7FET6	BARD1
4		iEKPD-Mod-0649	ENSMODG00000015150.2	F7CFT5	BRCA1
5		iEKPD-Mod-1285	ENSMODG00000011995.4	F7B931	CTDP1
6		iEKPD-Mod-0646	ENSMODG00000021319.3	F7FT66	ECT2
7		iEKPD-Mod-0647	ENSMODG00000025064.1	F6SA46	LIG4
8		iEKPD-Mod-0644	ENSMODG00000029065.1	K7E6B9	LOC100030017
9		iEKPD-Mod-0642	ENSMODG00000011537.4	F6QWV3	LOC100030030
10		iEKPD-Mod-1296	ENSMODG00000007677.3	F7B6C2	NBN
11		iEKPD-Mod-0654	ENSMODG00000006076.2	F7FES2	PARP1
12		iEKPD-Mod-0652	ENSMODG00000007894.3	F6YT84	PARP4
13		iEKPD-Mod-0643	ENSMODG00000004929.4	F7BGC3	PAXIP1
14		iEKPD-Mod-0656	ENSMODG00000011757.3	F7CWH7	POLL
15		iEKPD-Mod-0653	ENSMODG00000001409.3	F7BD34	REV1
16		iEKPD-Mod-0651	ENSMODG00000020548.3	F7BBS1	RFC1
17		iEKPD-Mod-0650	ENSMODG00000020124.3	F7DQV8	SLF1
18		iEKPD-Mod-0645	ENSMODG00000017806.3	F6ZY23	TP53BP1