Myotis lucifugus      (pS/pT)/BRCT


※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982


There are 20 genes.  Reviewed (0 or Unreviewed (20

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Myl-0650
ENSMLUG00000008972.2
G1PCR2
2
iEKPD-Myl-0655
ENSMLUG00000016959.2
G1PVT2
3
iEKPD-Myl-0654
ENSMLUG00000014140.2
G1PPD9
BARD1
4
iEKPD-Myl-0656
ENSMLUG00000004135.2
G1P1R4
BRCA1
5
iEKPD-Myl-1271
ENSMLUG00000011676.2
G1PIU1
CTDP1
6
iEKPD-Myl-0652
ENSMLUG00000013658.2
G1PNC4
ECT2
7
iEKPD-Myl-0663
ENSMLUG00000012470.2
G1PKN0
LIG3
8
iEKPD-Myl-0653
ENSMLUG00000001267.2
G1Q2N1
LIG4
9
iEKPD-Myl-0649
ENSMLUG00000014412.2
G1PPZ9
LOC102422576
10
iEKPD-Myl-0657
ENSMLUG00000006918.2
G1P852
LOC102427523
11
iEKPD-Myl-1277
ENSMLUG00000006271.2
G1P6N2
MDC1
12
iEKPD-Myl-1278
ENSMLUG00000008805.2
G1PCA2
NBN
13
iEKPD-Myl-0658
ENSMLUG00000003797.2
G1P109
PARP4
14
iEKPD-Myl-0651
ENSMLUG00000022696.1
G1PZL5
PAXIP1
15
iEKPD-Myl-0664
ENSMLUG00000004944.2
G1P3K8
POLL
16
iEKPD-Myl-0661
ENSMLUG00000008175.2
G1PAY4
REV1
17
iEKPD-Myl-0659
ENSMLUG00000013981.2
G1PP22
RFC1
18
iEKPD-Myl-0660
ENSMLUG00000009211.2
G1PD74
SLF1
19
iEKPD-Myl-0648
ENSMLUG00000005320.2
G1P4H6
TOPBP1
20
iEKPD-Myl-0662
ENSMLUG00000022404.1
G1Q9S0
XRCC1