※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Nef-0191	CADNFIAG00001596	A1D2B2	NFIA_012440
2		iEKPD-Nef-0187	CADNFIAG00003626	A1CZR5	NFIA_038090
3		iEKPD-Nef-0192	CADNFIAG00004248	A1DL70	NFIA_048780
4		iEKPD-Nef-0190	CADNFIAG00005152	A1DMQ5	NFIA_054220
5		iEKPD-Nef-0328	CADNFIAG00006560	A1D6T1	NFIA_065890
6		iEKPD-Nef-0186	CADNFIAG00007247	A1DDJ3	NFIA_073660
7		iEKPD-Nef-0188	CADNFIAG00008091	A1DDY8	NFIA_075240
8		iEKPD-Nef-0189	CADNFIAG00008037	A1DF96	NFIA_079950
9		iEKPD-Nef-0193	CADNFIAG00008345	A1DG99	NFIA_083580
10		iEKPD-Nef-0194	CADNFIAG00008588	A1DHC7	NFIA_087400
11		iEKPD-Nef-0185	CADNFIAG00009609	A1CWA7	NFIA_103970