※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Nia-0811	A4A49_12685	A0A1J6JJ54	A4A49_12685
2		iEKPD-Nia-0815	A4A49_14839	A0A1J6JCG0	A4A49_14839
3		iEKPD-Nia-0821	A4A49_18052	A0A1J6IBU1	A4A49_18052
4		iEKPD-Nia-0819	A4A49_22447	A0A1J6KZF9	A4A49_22447
5		iEKPD-Nia-0817	A4A49_25341	A0A1J6J7Z9	A4A49_25341
6		iEKPD-Nia-0814	A4A49_41640	A0A1J6JQJ8	A4A49_41640
7		iEKPD-Nia-0813	A4A49_15659	A0A1J6JNC6	BARD1_0; A4A49_15659
8		iEKPD-Nia-0812	A4A49_35047	A0A1J6JB20	BARD1_1; A4A49_35047
9		iEKPD-Nia-1033	A4A49_24011	A0A1J6KV98	CPL4; A4A49_24011
10		iEKPD-Nia-0820	A4A49_11704	A0A1J6ITJ4	PARP1; A4A49_11704
11		iEKPD-Nia-0818	A4A49_30233	A0A1J6JEB1	PARP3_0; A4A49_30233
12		iEKPD-Nia-0816	A4A49_27977	A0A1J6ICG2	XRCC1; A4A49_27977