※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Ocp-0597	ENSOPRG00000006456.1
2		iEKPD-Ocp-0598	ENSOPRG00000017067.2
3		iEKPD-Ocp-0599	ENSOPRG00000008283.2
4		iEKPD-Ocp-0600	ENSOPRG00000013212.1
5		iEKPD-Ocp-0601	ENSOPRG00000012405.2
6		iEKPD-Ocp-0602	ENSOPRG00000012295.1
7		iEKPD-Ocp-0603	ENSOPRG00000005765.1
8		iEKPD-Ocp-0605	ENSOPRG00000001938.1
9		iEKPD-Ocp-0606	ENSOPRG00000012895.1
10		iEKPD-Ocp-0607	ENSOPRG00000009077.1
11		iEKPD-Ocp-1114	ENSOPRG00000000378.1
12		iEKPD-Ocp-1111	ENSOPRG00000012357.1
13		iEKPD-Ocp-0608	ENSOPRG00000009989.1
14		iEKPD-Ocp-0609	ENSOPRG00000005257.1
15		iEKPD-Ocp-0610	ENSOPRG00000007391.1
16		iEKPD-Ocp-0611	ENSOPRG00000011722.1
17		iEKPD-Ocp-0612	ENSOPRG00000007162.1
18		iEKPD-Ocp-0613	ENSOPRG00000011746.1
19		iEKPD-Ocp-0614	ENSOPRG00000000636.1
20		iEKPD-Ocp-0604	ENSOPRG00000010889.1	Q8WMT6	BRCA1