※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Ora-0651	ENSOANG00000011210.3	F7FJ87
2		iEKPD-Ora-0652	ENSOANG00000029199.1	K7EGZ0
3		iEKPD-Ora-0653	ENSOANG00000005388.3	F6VGB2
4		iEKPD-Ora-1184	ENSOANG00000009014.2	F7EUB7
5		iEKPD-Ora-0657	ENSOANG00000013671.2	F7DMF3
6		iEKPD-Ora-0661	ENSOANG00000021425.1	F6Z2T4
7		iEKPD-Ora-0662	ENSOANG00000010767.3	F6Y2M2
8		iEKPD-Ora-1176	ENSOANG00000010132.3	F7F659	CTDP1
9		iEKPD-Ora-0655	ENSOANG00000019975.2	F6VV30	LOC100681780
10		iEKPD-Ora-0654	ENSOANG00000001316.3	F7FAC2	NBN
11		iEKPD-Ora-0660	ENSOANG00000001488.2	F7EUJ4	PARP1
12		iEKPD-Ora-0650	ENSOANG00000006152.4	F7BSM0	PAXIP1
13		iEKPD-Ora-0664	ENSOANG00000012901.3	F7BQD3	PES1
14		iEKPD-Ora-0663	ENSOANG00000007315.2	F6WYP8	POLL
15		iEKPD-Ora-0659	ENSOANG00000004622.2	F7FVX0	REV1
16		iEKPD-Ora-0658	ENSOANG00000010330.1	F6RMI6	RFC1
17		iEKPD-Ora-0656	ENSOANG00000011065.2	F7FKL7	SLF1
18		iEKPD-Ora-0649	ENSOANG00000006784.2	F6X8F8	TOPBP1