※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Osl-0185	OSTLU_14735	A4RUW3	OSTLU_14735
2		iEKPD-Osl-0188	OSTLU_16920	A4S365	OSTLU_16920
3		iEKPD-Osl-0190	OSTLU_1868	A4RS29	OSTLU_1868
4		iEKPD-Osl-0187	OSTLU_24500	A4RWX9	OSTLU_24500
5		iEKPD-Osl-0189	OSTLU_26270	A4S436	OSTLU_26270
6		iEKPD-Osl-0186	OSTLU_26493	A4S4Q6	OSTLU_26493
7		iEKPD-Osl-0183	OSTLU_26933	A4S5Z4	OSTLU_26933
8		iEKPD-Osl-0182	OSTLU_31098	A4RVU3	OSTLU_31098
9		iEKPD-Osl-0322	OSTLU_31186	A4RW22	OSTLU_31186
10		iEKPD-Osl-0184	OSTLU_32738	A4S0G7	OSTLU_32738