※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

  Reviewed (1)  or Unreviewed (11) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Phn-0185	SNOG_10525	Q0UCI9	LIG4; SNOG_10525
2		iEKPD-Phn-0189	SNOG_00745	Q0V5G9	SNOG_00745
3		iEKPD-Phn-0308	SNOG_00821	Q0V593	SNOG_00821
4		iEKPD-Phn-0186	SNOG_02255	Q0V159	SNOG_02255
5		iEKPD-Phn-0307	SNOG_03310	Q0UY54	SNOG_03310
6		iEKPD-Phn-0188	SNOG_07460	Q0ULA4	SNOG_07460
7		iEKPD-Phn-0187	SNOG_09459	Q0UFK5	SNOG_09459
8		iEKPD-Phn-0182	SNOG_10016	Q0UDZ8	SNOG_10016
9		iEKPD-Phn-0190	SNOG_10425	Q0UCT9	SNOG_10425
10		iEKPD-Phn-0184	SNOG_10565	Q0UCE9	SNOG_10565
11		iEKPD-Phn-0183	SNOG_11156	Q0UAQ8	SNOG_11156
12		iEKPD-Phn-0181	SNOG_15011	Q0TZK5	SNOG_15011