※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Poa-0640	ENSPPYG00000013144.2	H2P8H9	BARD1
2		iEKPD-Poa-0642	ENSPPYG00000008363.2	H2NTX3	BRCA1
3		iEKPD-Poa-1266	ENSPPYG00000009259.2	H2NWM9	CTDP1
4		iEKPD-Poa-0641	ENSPPYG00000014305.2	H2PC10	ECT2
5		iEKPD-Poa-0648	ENSPPYG00000008176.1	H2NTC2	LIG3; CR201_G0051899
6		iEKPD-Poa-0639	ENSPPYG00000005540.1	H2NKF6	LIG4
7		iEKPD-Poa-0638	ENSPPYG00000018317.2	H2PPE4	MCPH1
8		iEKPD-Poa-1273	ENSPPYG00000016418.2	H2PIG1	MDC1
9		iEKPD-Poa-1274	ENSPPYG00000018732.2	H2PQR7	NBN
10		iEKPD-Poa-0646	ENSPPYG00000000164.2	H2N3J1	PARP1
11		iEKPD-Poa-0635	ENSPPYG00000018210.2	H2PP48	PAXIP1; CR201_G0035696
12		iEKPD-Poa-0647	ENSPPYG00000011716.2	H2P423	PES1; CR201_G0024503
13		iEKPD-Poa-0649	ENSPPYG00000002584.2	H2NBD3	POLL; CR201_G0023535
14		iEKPD-Poa-0645	ENSPPYG00000012095.2	H2P576	REV1
15		iEKPD-Poa-0644	ENSPPYG00000014673.2	H2PD45	RFC1
16		iEKPD-Poa-0643	ENSPPYG00000015634.2	H2PG36	SLF1
17		iEKPD-Poa-0634	ENSPPYG00000014112.2	H2PBG6	TOPBP1
18		iEKPD-Poa-0636	ENSPPYG00000006414.2	H2NN14	TP53BP1
19		iEKPD-Poa-0637	ENSPPYG00000010063.2	H2NZ27	XRCC1