※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Put-0171	PTTG_08670	A0A180GEU5	NOP7; PTTG_08670
2		iEKPD-Put-0172	PTTG_00315	A0A180H1L3	PTTG_00315
3		iEKPD-Put-0167	PTTG_05093	A0A0C4EWA3	PTTG_05093
4		iEKPD-Put-0170	PTTG_00087	A0A180GXI9	PTTG_26209
5		iEKPD-Put-0168	PTTG_09532	A0A180GCM4	PTTG_28325
6		iEKPD-Put-0169	PTTG_08434	A0A180G9B9	PTTG_28808
7		iEKPD-Put-0166	PTTG_01033	A0A180G6K5	PTTG_29098