※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Pys-0189	PTT_07644	E3RI42	PTT_07644
2		iEKPD-Pys-0185	PTT_10147	E3RNJ7	PTT_10147
3		iEKPD-Pys-0192	PTT_10692	E3RPU5	PTT_10692
4		iEKPD-Pys-0182	PTT_11160	E3RQW8	PTT_11160
5		iEKPD-Pys-0322	PTT_11685	E3RS33	PTT_11685
6		iEKPD-Pys-0181	PTT_12211	E3RT94	PTT_12211
7		iEKPD-Pys-0186	PTT_14225	E3RXR6	PTT_14225
8		iEKPD-Pys-0184	PTT_14755	E3RYU6	PTT_14755
9		iEKPD-Pys-0321	PTT_14854	E3RZ15	PTT_14854
10		iEKPD-Pys-0187	PTT_16797	E3S310	PTT_16797
11		iEKPD-Pys-0191	PTT_17555	E3S4P1	PTT_17555
12		iEKPD-Pys-0183	PTT_17650	E3S4W2	PTT_17650
13		iEKPD-Pys-0190	PTT_18913	E3S7T1	PTT_18913
14		iEKPD-Pys-0188	PTT_20328	E3SAV2	PTT_20328