Schizosaccharomyces japonicus      (pS/pT)/BRCT


※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Scj-0175
SJAG_00882
B6JWV7
NOP7; SJAG_00882
2
iEKPD-Scj-0169
SJAG_01205
B6K016
SJAG_01205
3
iEKPD-Scj-0300
SJAG_01286
B6K094
SJAG_01286
4
iEKPD-Scj-0172
SJAG_01429
B6JXW7
SJAG_01429
5
iEKPD-Scj-0166
SJAG_02098
B6JZQ3
SJAG_02098
6
iEKPD-Scj-0173
SJAG_02240
B6K1X8
SJAG_02240
7
iEKPD-Scj-0170
SJAG_02527
B6K2R1
SJAG_02527
8
iEKPD-Scj-0168
SJAG_02837
B6K1B2
SJAG_02837
9
iEKPD-Scj-0174
SJAG_03090
B6K3A6
SJAG_03090
10
iEKPD-Scj-0171
SJAG_03906
B6K5D4
SJAG_03906
11
iEKPD-Scj-0167
SJAG_04142
B6K613
SJAG_04142