Schizosaccharomyces octosporus      (pS/pT)/BRCT


※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sco-0173
SOCG_00199
S9PTG9
SOCG_00199
2
iEKPD-Sco-0301
SOCG_00713
S9PZR4
SOCG_00713
3
iEKPD-Sco-0165
SOCG_00977
S9PZ20
SOCG_00977
4
iEKPD-Sco-0172
SOCG_01179
S9PTZ0
SOCG_01179
5
iEKPD-Sco-0171
SOCG_01390
S9PT80
SOCG_01390
6
iEKPD-Sco-0167
SOCG_01483
S9RAV3
SOCG_01483
7
iEKPD-Sco-0166
SOCG_01730
S9PVK0
SOCG_01730
8
iEKPD-Sco-0164
SOCG_02164
S9Q3N7
SOCG_02164
9
iEKPD-Sco-0163
SOCG_02672
S9Q159
SOCG_02672
10
iEKPD-Sco-0169
SOCG_03255
S9R716
SOCG_03255
11
iEKPD-Sco-0168
SOCG_03862
S9PRW5
SOCG_03862
12
iEKPD-Sco-0170
SOCG_04865
S9PW05
SOCG_04865