※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Scs-0127	SS1G_00911	A7E6I6	SS1G_00911
2		iEKPD-Scs-0126	SS1G_01299	A7E7M1	SS1G_01299
3		iEKPD-Scs-0122	SS1G_01751	A7E8X3	SS1G_01751
4		iEKPD-Scs-0128	SS1G_02275	A7EAE3	SS1G_02275
5		iEKPD-Scs-0123	SS1G_03342	A7EDF2	SS1G_03342
6		iEKPD-Scs-0124	SS1G_05603	A7EJV8	SS1G_05603
7		iEKPD-Scs-0125	SS1G_12346	A7F348	SS1G_12346
8		iEKPD-Scs-0121	SS1G_14422	A7F9Z1	SS1G_14422