※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sem-1443	SELMODRAFT_451419	D8RGA1	MEI1-1; SELMODRAFT_451419
2		iEKPD-Sem-1442	SELMODRAFT_446235	D8SPP9	MEI1-2; SELMODRAFT_446235
3		iEKPD-Sem-1459	SELMODRAFT_166421	D8QYP5	SELMODRAFT_166421
4		iEKPD-Sem-1460	SELMODRAFT_169468	D8R8Z2	SELMODRAFT_169468
5		iEKPD-Sem-1448	SELMODRAFT_403849	D8QSR0	SELMODRAFT_403849
6		iEKPD-Sem-1458	SELMODRAFT_403850	D8QSR1	SELMODRAFT_403850
7		iEKPD-Sem-1918	SELMODRAFT_405568	D8QZ05	SELMODRAFT_405568
8		iEKPD-Sem-1445	SELMODRAFT_406306	D8R1Y3	SELMODRAFT_406306
9		iEKPD-Sem-1455	SELMODRAFT_407478	D8R5R1	SELMODRAFT_407478
10		iEKPD-Sem-1440	SELMODRAFT_408510	D8R8J1	SELMODRAFT_408510
11		iEKPD-Sem-1917	SELMODRAFT_411029	D8RHS4	SELMODRAFT_411029
12		iEKPD-Sem-1446	SELMODRAFT_414166	D8RRV7	SELMODRAFT_414166
13		iEKPD-Sem-1444	SELMODRAFT_414577	D8RT82	SELMODRAFT_414577
14		iEKPD-Sem-1450	SELMODRAFT_415214	D8RVD9	SELMODRAFT_415214
15		iEKPD-Sem-1456	SELMODRAFT_416192	D8RYD3	SELMODRAFT_416192
16		iEKPD-Sem-1915	SELMODRAFT_418187	D8S4Y5	SELMODRAFT_418187
17		iEKPD-Sem-1457	SELMODRAFT_419110	D8S7V7	SELMODRAFT_419110
18		iEKPD-Sem-1921	SELMODRAFT_419113	D8S7W2	SELMODRAFT_419113
19		iEKPD-Sem-1453	SELMODRAFT_422701	D8SJ96	SELMODRAFT_422701
20		iEKPD-Sem-1447	SELMODRAFT_422836	D8SJP8	SELMODRAFT_422836
21		iEKPD-Sem-1441	SELMODRAFT_437359	D8QQE4	SELMODRAFT_437359
22		iEKPD-Sem-1916	SELMODRAFT_440109	D8RA55	SELMODRAFT_440109
23		iEKPD-Sem-1451	SELMODRAFT_440360	D8RBA0	SELMODRAFT_440360
24		iEKPD-Sem-1922	SELMODRAFT_443665	D8S3C6	SELMODRAFT_443665
25		iEKPD-Sem-1449	SELMODRAFT_443668	D8S3D1	SELMODRAFT_443668
26		iEKPD-Sem-1454	SELMODRAFT_445125	D8SFY4	SELMODRAFT_445125
27		iEKPD-Sem-1461	SELMODRAFT_447083	D8SWK9	SELMODRAFT_447083
28		iEKPD-Sem-1452	SELMODRAFT_73333	D8QNS9	SELMODRAFT_73333