※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

  Reviewed (0)  or Unreviewed (25) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sei-1533	Si004566m.g	K3XRM2	LOC101752606; SETIT_004566mg
2		iEKPD-Sei-1539	Si021018m.g	K3Z3A0	LOC101753210; SETIT_021018mg
3		iEKPD-Sei-1534	Si034223m.g	K4A5R9	LOC101755249; SETIT_034223mg
4		iEKPD-Sei-1535	Si005762m.g	K3XV05	LOC101755686; SETIT_005762mg
5		iEKPD-Sei-1857	Si019173m.g	K3YY23	LOC101757759; SETIT_019173mg
6		iEKPD-Sei-1537	Si034692m.g	K4A736	LOC101758903; SETIT_034692mg
7		iEKPD-Sei-1525	Si029423m.g	K3ZS43	LOC101759397; SETIT_029423mg
8		iEKPD-Sei-1861	Si034972m.g	K4A7W6	LOC101763098; SETIT_034972mg
9		iEKPD-Sei-1530	Si013596m.g	K3YH78	LOC101764105; SETIT_013596mg
10		iEKPD-Sei-1526	Si021105m.g	K3Z3I7	LOC101767419; SETIT_021105mg
11		iEKPD-Sei-1522	Si009617m.g	K3Y5X8	LOC101773588; SETIT_009617mg
12		iEKPD-Sei-1529	Si033996m.g	K4A542	LOC101775152; SETIT_033996mg
13		iEKPD-Sei-1536	Si025887m.g	K3ZH35	LOC101777540; SETIT_025887mg
14		iEKPD-Sei-1532	Si016357m.g	K3YQ15	LOC101777747; SETIT_016357mg
15		iEKPD-Sei-1531	Si028726m.g	K3ZQ46	LOC101778601; SETIT_028726mg
16		iEKPD-Sei-1541	Si006186m.g	K3XW78	LOC101782419; SETIT_006186mg
17		iEKPD-Sei-1540	Si029380m.g	K3ZS00	LOC101786800; SETIT_029380mg
18		iEKPD-Sei-1858	Si021686m.g	K3Z568	LOC101786822; SETIT_021686mg
19		iEKPD-Sei-1528	Si006812m.g	K3XY04	SETIT_006812mg
20		iEKPD-Sei-1523	Si009208m.g	K3Y4S0	SETIT_009208mg
21		iEKPD-Sei-1524	Si021914m.g	K3Z5U6	SETIT_021914mg
22		iEKPD-Sei-1527	Si021970m.g	K3Z602	SETIT_021970mg
23		iEKPD-Sei-1859	Si025879m.g	A0A0Q3UZE7	SETIT_0258791mg
24		iEKPD-Sei-1521	Si025914m.g	A0A0Q3QK33	SETIT_0259142mg
25		iEKPD-Sei-1538	Si039639m.g	K4AL59	SETIT_039639mg