※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sot-1348	PGSC0003DMG400012725	M1AYP5
2		iEKPD-Sot-1351	PGSC0003DMG400006140	M1A6F7
3		iEKPD-Sot-1354	PGSC0003DMG400007402	M1ABL8
4		iEKPD-Sot-1355	PGSC0003DMG400022845	M1C3B8
5		iEKPD-Sot-1357	PGSC0003DMG400007379	M1ABI8
6		iEKPD-Sot-1350	PGSC0003DMG400005381	M1A3A6	102579131
7		iEKPD-Sot-1358	PGSC0003DMG400017739	M1BI55	102581377
8		iEKPD-Sot-1349	PGSC0003DMG400016511	M1BD93	102582898
9		iEKPD-Sot-1356	PGSC0003DMG400006122	M1A6D6	102588856
10		iEKPD-Sot-1347	PGSC0003DMG400014714	M1B6E8	102589099
11		iEKPD-Sot-1346	PGSC0003DMG400009006	M1AI15	102594563
12		iEKPD-Sot-1352	PGSC0003DMG400026556	M1CIT8	102595855
13		iEKPD-Sot-1639	PGSC0003DMG400020522	M1BU42	102604136
14		iEKPD-Sot-1353	PGSC0003DMG401021989	M1BZM0	102606165