※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sus-0666	ENSSSCG00000016170.3	F1SSQ2	BARD1
2		iEKPD-Sus-0668	ENSSSCG00000022101.2	A0A286ZS33	BRCA1
3		iEKPD-Sus-1302	ENSSSCG00000005787.3	F1RWS7	CTDP1
4		iEKPD-Sus-0665	ENSSSCG00000035746.1	A0A287A8E7	ECT2
5		iEKPD-Sus-0676	ENSSSCG00000024770.2	I3L9T2	LIG3
6		iEKPD-Sus-0667	ENSSSCG00000009540.3	F1RLP1	LIG4
7		iEKPD-Sus-0670	ENSSSCG00000015754.3	F1RVK8	MCPH1
8		iEKPD-Sus-1309	ENSSSCG00000001362.4	K7GND6	MDC1
9		iEKPD-Sus-1310	ENSSSCG00000006127.4	A0A287AXZ9	NBN
10		iEKPD-Sus-0675	ENSSSCG00000023660.2	I3LDH3	PARP1
11		iEKPD-Sus-0671	ENSSSCG00000022957.2	I3LDB1	PARP4
12		iEKPD-Sus-0663	ENSSSCG00000025221.2	A0A286ZXL7	PAXIP1
13		iEKPD-Sus-0677	ENSSSCG00000010564.3	F1S8U1	POLL
14		iEKPD-Sus-0674	ENSSSCG00000008179.3	A0A287AD86	REV1
15		iEKPD-Sus-0673	ENSSSCG00000008788.3	A0A286ZJZ9	RFC1
16		iEKPD-Sus-0672	ENSSSCG00000014163.3	F1RNW0	SLF1
17		iEKPD-Sus-0662	ENSSSCG00000021966.2	A0A287BSI9	TOPBP1
18		iEKPD-Sus-0664	ENSSSCG00000031949.1	A0A287BBI2	TP53BP1
19		iEKPD-Sus-0669	ENSSSCG00000003055.3	A0A286ZV44	XRCC1