※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tag-0735	ENSTGUG00000004502.1	H0Z241
2		iEKPD-Tag-0742	ENSTGUG00000000723.1	H0YR28
3		iEKPD-Tag-0747	ENSTGUG00000015553.1	H0ZZ41
4		iEKPD-Tag-0739	ENSTGUG00000002894.1	H0YXG0	BARD1
5		iEKPD-Tag-0741	ENSTGUG00000002867.1	H0YXC9	BRCA1
6		iEKPD-Tag-1309	ENSTGUG00000006649.1	H0Z8E0	CTDP1
7		iEKPD-Tag-0738	ENSTGUG00000010794.1	H0ZKM2	ECT2
8		iEKPD-Tag-0740	ENSTGUG00000010795.1	H0ZKK3	LIG4
9		iEKPD-Tag-0737	ENSTGUG00000012890.1	H0ZRM8	MCPH1
10		iEKPD-Tag-1316	ENSTGUG00000011805.1	H0ZNJ4	NBN
11		iEKPD-Tag-0746	ENSTGUG00000004260.1	H0Z1I5	PARP1
12		iEKPD-Tag-0734	ENSTGUG00000000682.1	H0YQZ1	PAXIP1
13		iEKPD-Tag-0745	ENSTGUG00000009972.1	H0ZI77	POLL
14		iEKPD-Tag-0744	ENSTGUG00000010082.1	H0ZIJ6	REV1
15		iEKPD-Tag-0743	ENSTGUG00000008901.1	H0ZF59	RFC1
16		iEKPD-Tag-0736	ENSTGUG00000010331.1	H0ZJ98	TP53BP1