※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

  Reviewed (0)  or Unreviewed (12) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Trr-0173	TRIREDRAFT_120897	G0RF98	TRIREDRAFT_120897
2		iEKPD-Trr-0177	TRIREDRAFT_22115	G0RHK9	TRIREDRAFT_22115
3		iEKPD-Trr-0183	TRIREDRAFT_25225	G0R7G1	TRIREDRAFT_25225
4		iEKPD-Trr-0181	TRIREDRAFT_39156	G0RRX1	TRIREDRAFT_39156
5		iEKPD-Trr-0179	TRIREDRAFT_41794	G0R7W6	TRIREDRAFT_41794
6		iEKPD-Trr-0320	TRIREDRAFT_48686	G0RK60	TRIREDRAFT_48686
7		iEKPD-Trr-0175	TRIREDRAFT_58509	G0REV3	TRIREDRAFT_58509
8		iEKPD-Trr-0178	TRIREDRAFT_59346	G0RG78	TRIREDRAFT_59346
9		iEKPD-Trr-0176	TRIREDRAFT_60115	G0RHT5	TRIREDRAFT_60115
10		iEKPD-Trr-0174	TRIREDRAFT_64437	G0RNB4	TRIREDRAFT_64437
11		iEKPD-Trr-0182	TRIREDRAFT_64498	G0RNH6	TRIREDRAFT_64498
12		iEKPD-Trr-0180	TRIREDRAFT_75518	G0RCK9	TRIREDRAFT_75518