※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Usm-0147	UMAG_00290	A0A0D1CFS9	UMAG_00290
2		iEKPD-Usm-0149	UMAG_00389	A0A0D1E7X0	UMAG_00389
3		iEKPD-Usm-0269	UMAG_00568	A0A0D1ED52	UMAG_00568
4		iEKPD-Usm-0151	UMAG_02220	A0A0D1E5N9	UMAG_02220
5		iEKPD-Usm-0148	UMAG_03886	A0A0D1CM71	UMAG_03886
6		iEKPD-Usm-0150	UMAG_04676	A0A0D1DTH6	UMAG_04676