※ BRCT family introduction

    BRCA1 C-terminal (BRCT) domain was originally discovered as a domain conserved in multiple DNA damage-response proteins. Named after one of the founding members, BRCA1, BRCT domains are often found as tandem repeats within a single protein. BRCA1, 53BP1, DNA LIgase IV, and MDC1, for example, contain 2 BRCT domains, while MCPH1 contains 3, Pax-2 interacting protein (PTIP) contains 6, and TopBP1 contains 8. There are approximately thirty BRCT domain-containing proteins in mammalian cells, and essentially all of these appear to have roles in DNA damage signaling and DNA repair. It must be noted, however, that not all BRCT domains function as phosphopeptide binding modules (1).

Reference
1. Mohammad, D.H. (2009) 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response . DNA Repair, 8, 1009-17. PMID: 19481982

  Reviewed (2)  or Unreviewed (9) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Yal-0146	YALI0_D21384g	Q6C8A3	LIG4; YALI0D21384g
2		iEKPD-Yal-0151	YALI0_B23342g	Q6CDK0	NOP7; YALI0B23342g
3		iEKPD-Yal-0142	YALI0_B15576g	Q6CEH5	YALI0_B15576g
4		iEKPD-Yal-0150	YALI0_B16918g	Q6CEB7	YALI0_B16918g
5		iEKPD-Yal-0148	YALI0_D12364g	Q6C9C2	YALI0_D12364g
6		iEKPD-Yal-0149	YALI0_D19228g	Q6C8J0	YALI0_D19228g
7		iEKPD-Yal-0271	YALI0_E03278g	Q6C770	YALI0_E03278g
8		iEKPD-Yal-0147	YALI0_E16170g	Q6C5Q3	YALI0_E16170g
9		iEKPD-Yal-0143	YALI0_E21978g	Q6C511	YALI0_E21978g
10		iEKPD-Yal-0144	YALI0_E31273g	Q6C3Y4	YALI0_E31273g
11		iEKPD-Yal-0145	YALI0_F09141g	Q6C2B9	YALI0_F09141g