Homo sapiens      (pS/pT)/FF


※ FF family introduction

    FF domains were first identified in the murine splicing factor FBP11 (formin-binding protein 11) as a repeated sequence of about 60 amino acids containing two conserved phenylalanine (F) residues that give name to the domain. FF domains are primarily present in only the following three proteins: Prp40, FBP11, and CA150. Most interestingly, Prp40, FBP11, and CA150 have all been shown to recognize phospho-CTD-RNAPII repeats through their FF domains (1).

Reference
1. Gasch, A. (2006) The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains . J Biol Chem, 281, 356-64. PMID: 16253993


There are 4 genes.  Reviewed (4 or Unreviewed (0

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Hos-1335
ENSG00000196504.15
O75400
PRPF40A; FBP11; FLAF1; FNBP3; HIP10; HYPA; HSPC225
2
iEKPD-Hos-1336
ENSG00000110844.13
Q6NWY9
PRPF40B; HYPC
3
iEKPD-Hos-1334
ENSG00000113649.11
O14776
TCERG1; CA150; TAF2S
4
iEKPD-Hos-0687
ENSG00000176769.9
Q5VWI1
TCERG1L