Mus musculus      (pS/pT)/FF


※ FF family introduction

    FF domains were first identified in the murine splicing factor FBP11 (formin-binding protein 11) as a repeated sequence of about 60 amino acids containing two conserved phenylalanine (F) residues that give name to the domain. FF domains are primarily present in only the following three proteins: Prp40, FBP11, and CA150. Most interestingly, Prp40, FBP11, and CA150 have all been shown to recognize phospho-CTD-RNAPII repeats through their FF domains (1).

Reference
1. Gasch, A. (2006) The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains . J Biol Chem, 281, 356-64. PMID: 16253993


There are 4 genes.  Reviewed (4 or Unreviewed (0

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Mum-1331
ENSMUSG00000061136.14
Q9R1C7
Prpf40a; Fbp11; Fnbp3
2
iEKPD-Mum-1332
ENSMUSG00000023007.15
Q80W14
Prpf40b; Hypc
3
iEKPD-Mum-1330
ENSMUSG00000024498.15
Q8CGF7
Tcerg1; Taf2s
4
iEKPD-Mum-1333
ENSMUSG00000091002.2
Q3B807
Tcerg1l