Rattus norvegicus      (pS/pT)/FF


※ FF family introduction

    FF domains were first identified in the murine splicing factor FBP11 (formin-binding protein 11) as a repeated sequence of about 60 amino acids containing two conserved phenylalanine (F) residues that give name to the domain. FF domains are primarily present in only the following three proteins: Prp40, FBP11, and CA150. Most interestingly, Prp40, FBP11, and CA150 have all been shown to recognize phospho-CTD-RNAPII repeats through their FF domains (1).

Reference
1. Gasch, A. (2006) The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains . J Biol Chem, 281, 356-64. PMID: 16253993


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ran-1330
ENSRNOG00000004864.5
D3ZJ92
Prpf40a; Prpf40a_predicted; rCG_37769
2
iEKPD-Ran-1331
ENSRNOG00000052539.1
F1LTJ8
Prpf40b; RGD1565411_predicted; rCG_50817
3
iEKPD-Ran-1329
ENSRNOG00000018849.7
D3ZTL0
Tcerg1
4
iEKPD-Ran-1332
ENSRNOG00000016737.5
D4AE82
Tcerg1l; RGD1562437_predicted; rCG_48311