Chlorocebus sabaeus      (pS/pT)/GK


※ GK family introduction

    Membrane-associated guanylate kinases (MAGUKs) are a kind of scaffold proteins that play essential roles in tissue developments, cell–cell communications, cell polarity control, and cellular signal transductions. Despite extensive studies over the past two decades, the functions of the signature guanylate kinase domain (GK) of MAGUKs are poorly understood. However, recent study shows that the GK domain of DLG1/SAP97 binds to asymmetric cell division regulatory protein LGN in a phosphorylation-dependent manner (1).

Reference
1. Zhu, J. (2011) Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-bindingmodules. EMBO J, 30, 4986-97. PMID: 22117215


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Chs-1288
ENSCSAG00000008734.1
A0A0D9R8Q0
DLG1
2
iEKPD-Chs-1289
ENSCSAG00000003691.1
A0A0D9QUM2
DLG2
3
iEKPD-Chs-1290
ENSCSAG00000012054.1
A0A0D9RHZ8
DLG4