Dipodomys ordii      (pS/pT)/GK


※ GK family introduction

    Membrane-associated guanylate kinases (MAGUKs) are a kind of scaffold proteins that play essential roles in tissue developments, cell–cell communications, cell polarity control, and cellular signal transductions. Despite extensive studies over the past two decades, the functions of the signature guanylate kinase domain (GK) of MAGUKs are poorly understood. However, recent study shows that the GK domain of DLG1/SAP97 binds to asymmetric cell division regulatory protein LGN in a phosphorylation-dependent manner (1).

Reference
1. Zhu, J. (2011) Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-bindingmodules. EMBO J, 30, 4986-97. PMID: 22117215


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dio-1204
ENSDORG00000014475.2
A0A1S3FDS4
Dlg1
2
iEKPD-Dio-1205
ENSDORG00000010409.2
A0A1S3EZV6
Dlg2
3
iEKPD-Dio-1206
ENSDORG00000029363.1
A0A1S3EXB1
Dlg4