Mesocricetus auratus      (pS/pT)/GK


※ GK family introduction

    Membrane-associated guanylate kinases (MAGUKs) are a kind of scaffold proteins that play essential roles in tissue developments, cell–cell communications, cell polarity control, and cellular signal transductions. Despite extensive studies over the past two decades, the functions of the signature guanylate kinase domain (GK) of MAGUKs are poorly understood. However, recent study shows that the GK domain of DLG1/SAP97 binds to asymmetric cell division regulatory protein LGN in a phosphorylation-dependent manner (1).

Reference
1. Zhu, J. (2011) Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-bindingmodules. EMBO J, 30, 4986-97. PMID: 22117215


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Mea-1258
ENSMAUG00000022121.1
A0A1U8BRW9
Dlg1
2
iEKPD-Mea-1259
ENSMAUG00000012498.1
A0A1U8BWY2
Dlg2
3
iEKPD-Mea-1260
ENSMAUG00000019871.1
A0A1U8BLL6
Dlg4