Mustela putorius furo      (pS/pT)/GK


※ GK family introduction

    Membrane-associated guanylate kinases (MAGUKs) are a kind of scaffold proteins that play essential roles in tissue developments, cell–cell communications, cell polarity control, and cellular signal transductions. Despite extensive studies over the past two decades, the functions of the signature guanylate kinase domain (GK) of MAGUKs are poorly understood. However, recent study shows that the GK domain of DLG1/SAP97 binds to asymmetric cell division regulatory protein LGN in a phosphorylation-dependent manner (1).

Reference
1. Zhu, J. (2011) Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-bindingmodules. EMBO J, 30, 4986-97. PMID: 22117215


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Muf-1292
ENSMPUG00000008125.1
M3Y9R1
2
iEKPD-Muf-1291
ENSMPUG00000003769.1
M3XXD9
DLG1
3
iEKPD-Muf-1293
ENSMPUG00000010615.1
M3YGS9
DLG4