Pan troglodytes      (pS/pT)/GK


※ GK family introduction

    Membrane-associated guanylate kinases (MAGUKs) are a kind of scaffold proteins that play essential roles in tissue developments, cell–cell communications, cell polarity control, and cellular signal transductions. Despite extensive studies over the past two decades, the functions of the signature guanylate kinase domain (GK) of MAGUKs are poorly understood. However, recent study shows that the GK domain of DLG1/SAP97 binds to asymmetric cell division regulatory protein LGN in a phosphorylation-dependent manner (1).

Reference
1. Zhu, J. (2011) Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-bindingmodules. EMBO J, 30, 4986-97. PMID: 22117215


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pat-1410
ENSPTRG00000015793.7
A0A2I3RPZ4
DLG1; CK820_G0045912
2
iEKPD-Pat-1411
ENSPTRG00000004131.6
A0A2I3TX11
DLG2; CK820_G0021977
3
iEKPD-Pat-1412
ENSPTRG00000008663.6
H2QC23
DLG4; CK820_G0036839