※ MH2 family introduction

    The MAD Homology 2 domain found in SMADs binds phosphorylated SxxS motifs both in TGFb receptors and in each other. It is structurally related to the FHA domain (1)

Reference
1. http://kinase.com/wiki/index.php/Phospho-Serine/Threonine_binding_domains/

  Reviewed (8)  or Unreviewed (0) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Hos-0755	ENSG00000170365.9	Q15797	SMAD1; BSP1; MADH1; MADR1
2		iEKPD-Hos-0756	ENSG00000175387.15	Q15796	SMAD2; MADH2; MADR2
3		iEKPD-Hos-0759	ENSG00000166949.15	P84022	SMAD3; MADH3
4		iEKPD-Hos-0760	ENSG00000141646.13	Q13485	SMAD4; DPC4; MADH4
5		iEKPD-Hos-0758	ENSG00000113658.16	Q99717	SMAD5; MADH5
6		iEKPD-Hos-0762	ENSG00000137834.14	O43541	SMAD6; MADH6
7		iEKPD-Hos-0761	ENSG00000101665.8	O15105	SMAD7; MADH7; MADH8
8		iEKPD-Hos-0757	ENSG00000120693.13	O15198	SMAD9; MADH6; MADH9; SMAD8